Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7507
Gene Symbol: XPA
XPA 		0.320 GeneticVariation disease LHGDN XPA, haplotypes, and risk of basal and squamous cell carcinoma. 16513681 2006
Entrez Id: 7471
Gene Symbol: WNT1
WNT1 		0.010 AlteredExpression disease LHGDN WNT-1 expression in basal cell carcinoma of head and neck. An immunohistochemical and confocal study with regard to the intracellular distribution of beta-catenin. 12014624 2002
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 Biomarker disease MGD Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. 10545995 1999
Entrez Id: 4170
Gene Symbol: MCL1
MCL1 		0.010 AlteredExpression disease LHGDN The phosphotidyl inositol 3-kinase/Akt signal pathway is involved in interleukin-6-mediated Mcl-1 upregulation and anti-apoptosis activity in basal cell carcinoma cells. 12445202 2002
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.010 AlteredExpression disease LHGDN The phosphotidyl inositol 3-kinase/Akt signal pathway is involved in interleukin-6-mediated Mcl-1 upregulation and anti-apoptosis activity in basal cell carcinoma cells. 12445202 2002
Entrez Id: 5325
Gene Symbol: PLAGL1
PLAGL1 		0.010 AlteredExpression disease LHGDN The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas. 16179495 2005
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN Spectrum of PTCH mutations in Italian nevoid basal cell-carcinoma syndrome patients: identification of thirteen novel alleles. 15459969 2004
Entrez Id: 6662
Gene Symbol: SOX9
SOX9 		0.010 AlteredExpression disease LHGDN SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms. 18333897 2008
Entrez Id: 6608
Gene Symbol: SMO
SMO 		0.320 AlteredExpression disease LHGDN Significantly high levels of ultraviolet-specific mutations in the smoothened gene in basal cell carcinomas from DNA repair-deficient xeroderma pigmentosum patients. 12499255 2002
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L 		0.100 GeneticVariation disease GWASCAT Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. 19151717 2009
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3 		0.010 Biomarker disease LHGDN RUNX3 protein is overexpressed in human basal cell carcinomas. 16767156 2006
Entrez Id: 4613
Gene Symbol: MYCN
MYCN 		0.010 AlteredExpression disease LHGDN Recurrent NMYC copy number gain and high protein expression in basal cell carcinoma. 16596176 2006
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN PTCH1 and SMO gene alterations in keratocystic odontogenic tumors. 18502968 2008
Entrez Id: 6608
Gene Symbol: SMO
SMO 		0.320 GeneticVariation disease LHGDN PTCH1 and SMO gene alterations in keratocystic odontogenic tumors. 18502968 2008
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN PTCH mutations: distribution and analyses. 16419085 2006
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.600 GeneticVariation disease LHGDN PTCH germline mutations in Chinese nevoid basal cell carcinoma syndrome patients. 18302678 2008
Entrez Id: 7507
Gene Symbol: XPA
XPA 		0.320 GeneticVariation disease LHGDN Polymorphisms in nucleotide excision repair genes, arsenic exposure, and non-melanoma skin cancer in New Hampshire. 17687452 2007
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.020 GeneticVariation disease LHGDN Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes. 17307204 2007
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		0.310 GeneticVariation disease LHGDN Polymorphism in the nuclear excision repair gene ERCC2/XPD: association between an exon 6-exon 10 haplotype and susceptibility to cutaneous basal cell carcinoma. 15776433 2005
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.010 AlteredExpression disease LHGDN Pigmentation in basal cell carcinoma involves enhanced endothelin-1 expression. 15946241 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.130 AlteredExpression disease LHGDN Phosphorylation state of tumor-suppressor gene p53 product overexpressed in skin tumors. 15492790 2004
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.020 AlteredExpression disease LHGDN p16 gene expression in basal cell carcinoma. 18760195 2008
Entrez Id: 2735
Gene Symbol: GLI1
GLI1 		0.030 AlteredExpression disease LHGDN Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes. 16434164 2006
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		0.010 AlteredExpression disease LHGDN Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma. 18547788 2008
Entrez Id: 1386
Gene Symbol: ATF2
ATF2 		0.010 AlteredExpression disease LHGDN Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma. 18547788 2008